What’s the best bet to make, looking at each of the 16 games on the NFL’s Week 13 slate? Our favorite point-spread pick is Buccaneers -6, but we have plenty more tips for you, which could lead to parlay possibilities, below.

Take advantage of our predictions to make your NFL picks this week. BetMGM has all the information you need to begin betting on the NFL.

Best Week 13 Spread Bets

Jump to Matchup:

LAC-ATL | SEA-NYJ | IND-NE | MIA-GB | PIT-CIN

Pick: Chargers -1.5 vs. Falcons

• Matchup: Los Angeles Chargers at Atlanta Falcons
• Projected Winner & Margin: Chargers by 3.1 points (Bet on this game at BetMGM)
• Spread: Chargers -1.5
• Time: 1 p.m. ET
• Date: Dec. 1
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Pick: Seahawks -2 vs. Jets

• Matchup: Seattle Seahawks at New York Jets
• Projected Winner & Margin: Seahawks by 4.0 points (Bet on this game at BetMGM)
• Spread: Seahawks -2
• Time: 1 p.m. ET
• Date: Dec. 1
• TV Channel: FOX
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Colts -2.5 vs. Patriots

• Matchup: Indianapolis Colts at New England Patriots
• Projected Winner & Margin: Colts by 5.4 points (Bet on this game at BetMGM)
• Spread: Colts -2.5
• Time: 1 p.m. ET
• Date: Dec. 1
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Pick: Packers -3 vs. Dolphins

• Matchup: Miami Dolphins at Green Bay Packers
• Projected Winner & Margin: Packers by 16.6 points (Bet on this game at BetMGM)
• Spread: Packers -3
• Time: 8:20 p.m. ET
• Date: Nov. 28
• TV Channel: NBC
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Steelers +3 vs. Bengals

• Matchup: Pittsburgh Steelers at Cincinnati Bengals
• Projected Winner & Margin: Steelers by 5.0 points (Bet on this game at BetMGM)
• Spread: Bengals -3
• Time: 1 p.m. ET
• Date: Dec. 1
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Make smart decisions. Use those stats when making your NFL picks and place your bet on BetMGM.

Best Week 13 Total Bets

Jump to Matchup:

Under 51 – Eagles vs. Ravens

• Matchup: Philadelphia Eagles at Baltimore Ravens
• Projected Total: 49.9 points (Bet on this game at BetMGM)
• Time: 4:25 p.m. ET
• Date: Dec. 1
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Under 45.5 – Cardinals vs. Vikings

• Matchup: Arizona Cardinals at Minnesota Vikings
• Projected Total: 43.2 points (Bet on this game at BetMGM)
• Time: 1 p.m. ET
• Date: Dec. 1
• TV Channel: FOX
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Under 48.5 – Bears vs. Lions

• Matchup: Chicago Bears at Detroit Lions
• Projected Total: 44.6 points (Bet on this game at BetMGM)
• Time: 12:30 p.m. ET
• Date: Nov. 28
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Over 45 – 49ers vs. Bills

• Matchup: San Francisco 49ers at Buffalo Bills
• Projected Total: 47.9 points (Bet on this game at BetMGM)
• Time: 8:20 p.m. ET
• Date: Dec. 1
• TV Channel: NBC
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Under 47 – Dolphins vs. Packers

• Matchup: Miami Dolphins at Green Bay Packers
• Projected Total: 43.7 points (Bet on this game at BetMGM)
• Time: 8:20 p.m. ET
• Date: Nov. 28
• TV Channel: NBC
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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