Based on our projections, the best bet against the spread among Week 11’s 50 FBS games is Notre Dame (-4.5) — for more tips, including parlay opportunities, see below.

Look for computer picks and insights for that matchup and more in this article.

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College Football Computer Picks – Best Spread Bets

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Pick: Notre Dame -4.5 vs. Florida State

• Matchup: Florida State Seminoles at Notre Dame Fighting Irish
• Projected Winner & Margin: Notre Dame by 30.9 points
• Time: 7:30 PM ET
• Date: Nov. 9
• TV Channel: NBC
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Ole Miss +6.5 vs. Georgia

• Matchup: Georgia Bulldogs at Ole Miss Rebels
• Projected Winner & Margin: Ole Miss by 5 points
• Time: 3:30 PM ET
• Date: Nov. 9
• TV Channel: ABC
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Virginia Tech +4.5 vs. Clemson

• Matchup: Clemson Tigers at Virginia Tech Hokies
• Projected Winner & Margin: Virginia Tech by 4.4 points
• Time: 3:30 PM ET
• Date: Nov. 9
• TV Channel: ESPN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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College Football Computer Picks – Best Total Bets

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